Adipose-derived stem cell sheets accelerate bone healing in rat femoral defects.

In the present study, we investigated whether both adipose-derived stem cell (ADSC) and osteogenic-induced ADSC sheets could promote bone healing in a rat distal femoral metaphysis bone defect model. A through-hole defect of 1 mm diameter was drilled into each distal femur of 12 week old rats. Forty...

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Bibliographic Details
Main Authors: Yasuhisa Yoshida, Hidenori Matsubara, Xiang Fang, Katsuhiro Hayashi, Issei Nomura, Shuhei Ugaji, Tomo Hamada, Hiroyuki Tsuchiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214488