Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis
Diabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN.
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De Gruyter
2021-09-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2021-0328 |
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doaj-929d2e0dac2346f6a54c52bf927f9c6d2021-10-03T07:42:38ZengDe GruyterOpen Medicine2391-54632021-09-011611336134910.1515/med-2021-0328Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axisDong Qianlan0Wang Qiong1Yan Xiaohui2Wang Xiaoming3Li Zhenjiang4Zhang Linping5Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaDiabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN.https://doi.org/10.1515/med-2021-0328miatdnmir-182-5pgprc5anf-κb pathway |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping |
| spellingShingle |
Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis Open Medicine miat dn mir-182-5p gprc5a nf-κb pathway |
| author_facet |
Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping |
| author_sort |
Dong Qianlan |
| title |
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_short |
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_full |
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_fullStr |
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_full_unstemmed |
Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_sort |
long noncoding rna miat inhibits the progression of diabetic nephropathy and the activation of nf-κb pathway in high glucose-treated renal tubular epithelial cells by the mir-182-5p/gprc5a axis |
| publisher |
De Gruyter |
| series |
Open Medicine |
| issn |
2391-5463 |
| publishDate |
2021-09-01 |
| description |
Diabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN. |
| topic |
miat dn mir-182-5p gprc5a nf-κb pathway |
| url |
https://doi.org/10.1515/med-2021-0328 |
| work_keys_str_mv |
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1716845971093061632 |