Spontaneous formation and base pairing of plausible prebiotic nucleotides in water

One of the questions for prebiotic chemistry is the formation of complementary base pairing systems. Here, the authors show that plausible two prebiotic heterocycles can form glycosidic bonds with ribose in water and that these spontaneously base-pair in aqueous solution.

Bibliographic Details
Main Authors: Brian J. Cafferty, David M. Fialho, Jaheda Khanam, Ramanarayanan Krishnamurthy, Nicholas V. Hud
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11328