Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Bibliographic Details
Main Authors:	Dr. A. Toure, M. Cabral, A. Niang, C. Diop, A. Garat, L. Humbert, M. Fall, A. Diouf, F. Broly, M. Lhermitte, D. Allorge
Format:	Article
Language:	English
Published:	Elsevier 2016-01-01
Series:	Toxicology Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214750016300804

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