Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of <i>Klebsiella pneumoniae</i> Producers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK

Mechanisms of Tolerance and Resistance to Chlorhexidine in Clinical Strains of <i>Klebsiella pneumoniae</i> Producers of Carbapenemase: Role of New Type II Toxin-Antitoxin System, PemIK

Although the failure of antibiotic treatment is normally attributed to resistance, tolerance and persistence display a significant role in the lack of response to antibiotics. Due to the fact that several nosocomial pathogens show a high level of tolerance and/or resistance to chlorhexidine, in this...

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Bibliographic Details
Main Authors: Ines Bleriot, Lucia Blasco, Mercedes Delgado-Valverde, Ana Gual de Torella, Anton Ambroa, Laura Fernandez-Garcia, Maria Lopez, Jesus Oteo-Iglesias, Thomas K. Wood, Alvaro Pascual, German Bou, Felipe Fernandez-Cuenca, Maria Tomas
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Toxins
Subjects:
tolerance
persistence
cross-resistance
toxin-antitoxin system
PemI/PemK
<i>Klebsiella pneumoniae</i>
Online Access:https://www.mdpi.com/2072-6651/12/9/566

Internet

https://www.mdpi.com/2072-6651/12/9/566

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