Unilateral Hydronephrosis and Renal Damage after Acute Leukemia

Unilateral Hydronephrosis and Renal Damage after Acute Leukemia

A 14-year-old boy presented with asymptomatic right hydronephrosis detected on routine yearly ultrasound examination. Previously, he had at least two normal renal ultrasonograms, 4 years after remission of acute myeloblastic leukemia, treated by AML-BFM-93 protocol. A function of the right kidney an...

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Main Authors: Egle Simanauskiene, Valentina Daugelaviciene, Arvydas Laurinavicius, Ugnius Mickys, Vaida Simonyte, Goda Vaitkeviciene, Gilvydas Verkauskas
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/968491
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spelling doaj-9292ab1a1e2c4704913ba0613bb4eed42020-11-24T23:14:54ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/968491968491Unilateral Hydronephrosis and Renal Damage after Acute LeukemiaEgle Simanauskiene0Valentina Daugelaviciene1Arvydas Laurinavicius2Ugnius Mickys3Vaida Simonyte4Goda Vaitkeviciene5Gilvydas Verkauskas6Children's Hospital, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 7, 08406 Vilnius, LithuaniaChildren's Hospital, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 7, 08406 Vilnius, LithuaniaNational Center of Pathology, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 2, 08661 Vilnius, LithuaniaNational Center of Pathology, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 2, 08661 Vilnius, LithuaniaNational Center of Pathology, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 2, 08661 Vilnius, LithuaniaChildren's Hospital, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 7, 08406 Vilnius, LithuaniaChildren's Hospital, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 7, 08406 Vilnius, LithuaniaA 14-year-old boy presented with asymptomatic right hydronephrosis detected on routine yearly ultrasound examination. Previously, he had at least two normal renal ultrasonograms, 4 years after remission of acute myeloblastic leukemia, treated by AML-BFM-93 protocol. A function of the right kidney and no damage on the left was confirmed by a DMSA scan. Right retroperitoneoscopic nephrectomy revealed 3 renal arteries with the lower pole artery lying on the pelviureteric junction. Histologically chronic tubulointerstitial nephritis was detected. In the pathogenesis of this severe unilateral renal damage, we suspect the exacerbation of deleterious effects of cytostatic therapy on kidneys with intermittent hydronephrosis.http://dx.doi.org/10.1155/2012/968491
collection DOAJ
language English
format Article
sources DOAJ
author Egle Simanauskiene
Valentina Daugelaviciene
Arvydas Laurinavicius
Ugnius Mickys
Vaida Simonyte
Goda Vaitkeviciene
Gilvydas Verkauskas
spellingShingle Egle Simanauskiene
Valentina Daugelaviciene
Arvydas Laurinavicius
Ugnius Mickys
Vaida Simonyte
Goda Vaitkeviciene
Gilvydas Verkauskas
Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
Case Reports in Medicine
author_facet Egle Simanauskiene
Valentina Daugelaviciene
Arvydas Laurinavicius
Ugnius Mickys
Vaida Simonyte
Goda Vaitkeviciene
Gilvydas Verkauskas
author_sort Egle Simanauskiene
title Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
title_short Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
title_full Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
title_fullStr Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
title_full_unstemmed Unilateral Hydronephrosis and Renal Damage after Acute Leukemia
title_sort unilateral hydronephrosis and renal damage after acute leukemia
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2012-01-01
description A 14-year-old boy presented with asymptomatic right hydronephrosis detected on routine yearly ultrasound examination. Previously, he had at least two normal renal ultrasonograms, 4 years after remission of acute myeloblastic leukemia, treated by AML-BFM-93 protocol. A function of the right kidney and no damage on the left was confirmed by a DMSA scan. Right retroperitoneoscopic nephrectomy revealed 3 renal arteries with the lower pole artery lying on the pelviureteric junction. Histologically chronic tubulointerstitial nephritis was detected. In the pathogenesis of this severe unilateral renal damage, we suspect the exacerbation of deleterious effects of cytostatic therapy on kidneys with intermittent hydronephrosis.
url http://dx.doi.org/10.1155/2012/968491
work_keys_str_mv AT eglesimanauskiene unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT valentinadaugelaviciene unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT arvydaslaurinavicius unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT ugniusmickys unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT vaidasimonyte unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT godavaitkeviciene unilateralhydronephrosisandrenaldamageafteracuteleukemia
AT gilvydasverkauskas unilateralhydronephrosisandrenaldamageafteracuteleukemia
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