Runx1 is critical for PTH-induced onset of mesenchymal progenitor cell chondrogenic differentiation.

Runx1 is critical for PTH-induced onset of mesenchymal progenitor cell chondrogenic differentiation.

Parathyroid hormone (PTH) plays a critical role in the regulation of chondrogenesis. In this study, we have found for the first time that Runt-related transcription factor 1 (Runx1) contributes to PTH-induced chondrogenesis. Upon PTH treatment, limb bud mesenchymal progenitor cells in micromass cult...

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Bibliographic Details
Main Authors: Jinwu Wang, Xudong Wang, Jonathan D Holz, Timothy Rutkowski, Yongjun Wang, Zhenan Zhu, Yufeng Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776859?pdf=render

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