Comparative Solid-State Stability of Perindopril Active Substance vs. Pharmaceutical Formulation

Comparative Solid-State Stability of Perindopril Active Substance vs. Pharmaceutical Formulation

This paper presents the results obtained after studying the thermal stability and decomposition kinetics of perindopril erbumine as a pure active pharmaceutical ingredient as well as a solid pharmaceutical formulation containing the same active pharmaceutical ingredient (API). Since no data were fou...

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Bibliographic Details
Main Authors: Valentina Buda, Minodora Andor, Adriana Ledeti, Ionut Ledeti, Gabriela Vlase, Titus Vlase, Carmen Cristescu, Mirela Voicu, Liana Suciu, Mirela Cleopatra Tomescu
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:International Journal of Molecular Sciences
Subjects:
perindopril erbumine
perindopril tert-butylamine
thermal stability
decomposition
pharmaceutical formulation
comparative stability
isoconversional kinetic study
ASTM E698
Online Access:http://www.mdpi.com/1422-0067/18/1/164

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http://www.mdpi.com/1422-0067/18/1/164

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