Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

<h4>Background</h4>Demyelination and axonal damage are critical processes in the pathogenesis of multiple sclerosis (MS). Oxidative stress and pro-inflammatory cytokines elicited by inflammation mediates tissue damage.<h4>Methods/principal findings</h4>To monitor the demyelin...

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Bibliographic Details
Main Authors: Alessandra di Penta, Beatriz Moreno, Stephanie Reix, Begoña Fernandez-Diez, Maite Villanueva, Oihana Errea, Nagore Escala, Koen Vandenbroeck, Joan X Comella, Pablo Villoslada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23431360/?tool=EBI

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