Declarative and procedural learning in children and adolescents with posterior fossa tumours

• Main Authors: Casares Encarnación, Gómez Carlos M, Quintero-Gallego Eliana A, Márquez Javier, Pérez-Santamaría Fco
• Format: Article
• Language: English
• Published: BMC 2006-03-01
• Series: Behavioral and Brain Functions
• Online Access: http://www.behavioralandbrainfunctions.com/content/2/1/9

<p>Abstract</p> <p>Background</p> <p>This quasi-experimental study was designed to assess two important learning types – procedural and declarative – in children and adolescents affected by posterior fossa tumours (astrocytoma vs. medulloblastoma), given that memory has an important impact on the child's academic achievement and personal development.</p> <p>Methods</p> <p>We had three groups: two clinical (eighteen subjects) and one control (twelve subjects). The learning types in these groups were assessed by two experimental tasks evaluating procedural-implicit and declarative memory. A Serial Reaction-Time Task was used to measure procedural sequence learning, and the Spanish version <abbrgrp><abbr bid="B1">1</abbr></abbrgrp> of the California Verbal Learning Test-Children's Version- CVLT- <abbrgrp><abbr bid="B2">2</abbr></abbrgrp> to measure declarative-explicit learning. The learning capacity was assessed considering only the blocks that represent learning, and were compared with MANOVA in clinical and normal subjects. The Raven, simple reaction-time, finger-tapping test, and grooved pegboard tests were used to assess the overall functioning of subjects. The results were compared with those from a control group of the same age, and with Spanish norm-referenced tools where available</p> <p>Results</p> <p>The results indicate the absence of procedural-implicit learning in both clinical groups, whereas declarative-explicit learning is maintained in both groups.</p> <p>Conclusion</p> <p>The clinical groups showed a conservation of declarative learning and a clear impairment of procedural learning. The results support the role of the cerebellum in the early phase of procedural learning.</p>