Articular chondrocytes from osteoarthritic knee joints of elderly, in vitro expanded in thermo-reversible gelation polymer (TGP), exhibiting higher UEA-1 expression in lectin microarray

Articular chondrocytes from osteoarthritic knee joints of elderly, in vitro expanded in thermo-reversible gelation polymer (TGP), exhibiting higher UEA-1 expression in lectin microarray

Autologous chondrocytes in vitro expanded, are used as tools of regenerative therapies for cartilage injuries. However, inability to maintain the hyaline phenotype both in vitro and post in vivo transplantation, remains one of the major hurdles for long term efficacy under clinical settings. We have...

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Bibliographic Details
Main Authors: Shojiro Katoh, Atsuki Fujimaru, Rajappa Senthilkumar, Senthilkumar Preethy, Samuel JK. Abraham
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Regenerative Therapy
Subjects:
Cartilage
Chondrocytes
Osteoarthritis
Thermo-reversible gelation polymer (TGP) scaffold
Hyaline phenotype
Pluripotency
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300274

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