Protective Effect of Time-Modulated Cimetidine on Methotrexate-induced Liver Toxicity

Protective Effect of Time-Modulated Cimetidine on Methotrexate-induced Liver Toxicity

Background: Methotrexate (MTX) is one of the frequently used chemotherapeutic agents, especially in hematological malignancies and solid tumors. Objectives: MTX hepatotoxicity symptoms range from elevations in serum aminotransferases to hepatocyte necrosis and fibrosis. The time of medication admini...

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Bibliographic Details
Main Authors: Elias Adikwu, Emmanuel Nnaedozie
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2020-06-01
Series:Pharmaceutical and Biomedical Research
Subjects:
methotrexate
liver
toxicity
cimetidine
time
Online Access:http://pbr.mazums.ac.ir/article-1-267-en.html

Internet

http://pbr.mazums.ac.ir/article-1-267-en.html

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