A Novel Strategy for Detection and Enumeration of Circulating Rare Cell Populations in Metastatic Cancer Patients Using Automated Microfluidic Filtration and Multiplex Immunoassay.

A Novel Strategy for Detection and Enumeration of Circulating Rare Cell Populations in Metastatic Cancer Patients Using Automated Microfluidic Filtration and Multiplex Immunoassay.

Size selection via filtration offers an antigen-independent approach for the enrichment of rare cell populations in blood of cancer patients. We evaluated the performance of a novel approach for multiplex rare cell detection in blood samples from metastatic breast (n = 19) and lung cancer patients (...

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Bibliographic Details
Main Authors: Mark Jesus M Magbanua, Michael Pugia, Jin Sun Lee, Marc Jabon, Victoria Wang, Matthew Gubens, Karen Marfurt, Julia Pence, Harwinder Sidhu, Arejas Uzgiris, Hope S Rugo, John W Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619669?pdf=render

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