Blocking Autophagic Flux Enhances Matrine-Induced Apoptosis in Human Hepatoma Cells

Autophagy, a self-defense mechanism, has been found to be associated with drug resistance in hepatocellular carcinoma (HCC). Our study was designed to investigate the role and related mechanisms of autophagy in matrine-induced apoptosis in hepatoma cells of HepG2 and Bel7402. Cell apoptosis was dete...

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Bibliographic Details
Main Authors: Li Wang, Chun Gao, Shukun Yao, Bushan Xie
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/12/23212