Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming

Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming

Segregation of an MSH1 RNAi transgene produces non-genetic memory that displays transgenerational inheritance in Arabidopsis. Here, the authors compare memory and non-memory full-sib progenies to show the involvement of DNA methylation reprogramming, involving the RdDM pathway, in transition to a he...

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Main Authors: Xiaodong Yang, Robersy Sanchez, Hardik Kundariya, Tom Maher, Isaac Dopp, Rosemary Schwegel, Kamaldeep Virdi, Michael J. Axtell, Sally A. Mackenzie
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16036-8
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spelling doaj-924ba34b105b45789ab00901c02f7fdd2021-05-11T08:39:17ZengNature Publishing GroupNature Communications2041-17232020-05-0111111710.1038/s41467-020-16036-8Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogrammingXiaodong Yang0Robersy Sanchez1Hardik Kundariya2Tom Maher3Isaac Dopp4Rosemary Schwegel5Kamaldeep Virdi6Michael J. Axtell7Sally A. Mackenzie8Departments of Biology and Plant Science, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversityDepartment of Agronomy and Horticulture, University of NebraskaDepartment of Biology, The Pennsylvania State UniversityDepartments of Biology and Plant Science, The Pennsylvania State UniversitySegregation of an MSH1 RNAi transgene produces non-genetic memory that displays transgenerational inheritance in Arabidopsis. Here, the authors compare memory and non-memory full-sib progenies to show the involvement of DNA methylation reprogramming, involving the RdDM pathway, in transition to a heritable memory state.https://doi.org/10.1038/s41467-020-16036-8
collection DOAJ
language English
format Article
sources DOAJ
author Xiaodong Yang
Robersy Sanchez
Hardik Kundariya
Tom Maher
Isaac Dopp
Rosemary Schwegel
Kamaldeep Virdi
Michael J. Axtell
Sally A. Mackenzie
spellingShingle Xiaodong Yang
Robersy Sanchez
Hardik Kundariya
Tom Maher
Isaac Dopp
Rosemary Schwegel
Kamaldeep Virdi
Michael J. Axtell
Sally A. Mackenzie
Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
Nature Communications
author_facet Xiaodong Yang
Robersy Sanchez
Hardik Kundariya
Tom Maher
Isaac Dopp
Rosemary Schwegel
Kamaldeep Virdi
Michael J. Axtell
Sally A. Mackenzie
author_sort Xiaodong Yang
title Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
title_short Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
title_full Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
title_fullStr Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
title_full_unstemmed Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
title_sort segregation of an msh1 rnai transgene produces heritable non-genetic memory in association with methylome reprogramming
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-05-01
description Segregation of an MSH1 RNAi transgene produces non-genetic memory that displays transgenerational inheritance in Arabidopsis. Here, the authors compare memory and non-memory full-sib progenies to show the involvement of DNA methylation reprogramming, involving the RdDM pathway, in transition to a heritable memory state.
url https://doi.org/10.1038/s41467-020-16036-8
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