Acute-phase serum amyloid a in osteoarthritis: regulatory mechanism and proinflammatory properties.

OBJECTIVE: To determine if serum amyloid A (A-SAA) could be detected in human osteoarthritic (OA) joints and further clarify if high A-SAA level in joints result from a local production or from a diffusion process from abnormally elevated plasma concentration. Regulatory mechanism of A-SAA expressio...

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Bibliographic Details
Main Authors: Dominique de Seny, Gaël Cobraiville, Edith Charlier, Sophie Neuville, Nathalie Esser, Denis Malaise, Olivier Malaise, Florence Quesada Calvo, Biserka Relic, Michel G Malaise
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3680431?pdf=render