Risk factors associated with arterial hypertension in patients with systemic lupus erythematosus. Holguín, Cuba

• Main Authors: Raisa Rodríguez Hernández, Alberto Alberteris Rodríguez, Jackeline López Báster, Mariela Diéguez Martínez, Pedro Enrique Miguel-Soca, Yudelkis Cutié Anido
• Format: Article
• Language: English
• Published: Universidad de Ciencias Médicas de La Habana 2018-05-01
• Series: Revista Habanera de Ciencias Médicas
• Online Access: http://www.revhabanera.sld.cu/index.php/rhab/article/view/2335

<p style="margin-bottom: .0001pt; text-align: justify; line-height: 150%;"><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Introduction:</strong> The presence of arterial hypertension in patients with systemic lupus erythematosus is a health problem that has not been studied in Holguín.<br /> </span><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Objective:</strong> To determine the cardiovascular risk factors associated with hypertension in patients with systemic lupus erythematosus.<br /> </span><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Material and Methods:</strong> A cross-sectional study was conducted. The universe was composed of 193 patients with lupus who were treated in the Rheumatology Consultation of the Clinical-Surgical Hospital of Holguín from March 3, 2014 to January 1, 2015. The sample was made up of 81 patients who were randomly selected according to a 95 % confidence interval, a population size of 193, an estimated proportion of arterial hypertension of 0,20, a precision of a 7 %, and a design effect of 1.  The recommendations of the <em>American College of Rheumatology</em> were followed for the diagnosis of lupus erythematosus, and national guidelines were used for the diagnosis of hypertension.  Clinical, anthropometric, and laboratory variables were determined. <em>Odds Ratio</em> (OR), and 95 % confidence intervals (IC95%) for risk determined factors were.<br /> </span><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Results:</strong> The risk factors associated with hypertension in patients with lupus erythematosus are: age (OR=1,04; IC95%:1,01-1,08), age of the lupus onset (OR=1,04; IC95%:1,01-1,08), diabetes mellitus (OR=8,50; IC95%:1,63-44,33), metabolic syndrome (OR=5,09; IC95%:1,87-13,84), hyperuricemia (OR=4,08; IC95%:1,07-15,44), and microalbuminuria (OR=19,81; IC95%:4,24-92,39).<br /> </span><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Conclusions:</strong> The patients with systemic lupus erythematosus presented cardiovascular risk factors associated with arterial hypertension, which are identifiable in the primary health care with variables of relatively easy realization. </span></p><p style="margin-bottom: .0001pt; text-align: justify; line-height: 150%;"><span style="color: #000000; font-family: verdana; font-size: small;"><strong>Keywords:</strong> systemic lupus erythematosus, metabolic syndrome, hypertension, risk factors, adults.</span></p>