Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.

Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.

Analysis of acetylation and tri-methylation of the same residue of histone molecules might identify a subset of hepatocellular carcinoma (HCC) with aggressive behavior. In the present study, we examined acetylation and tri-methylation of lysine 27 on histone H3 (H3K27ac and H3K27me3, respectively) b...

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Main Authors: Akimasa Hayashi, Naoko Yamauchi, Junji Shibahara, Hiroshi Kimura, Teppei Morikawa, Shumpei Ishikawa, Genta Nagae, Akihiro Nishi, Yoshihiro Sakamoto, Norihiro Kokudo, Hiroyuki Aburatani, Masashi Fukayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948868?pdf=render

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