Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease in developed countries, and in recent years, the prevalence rate of NAFLD tends to increase in China, which brings heavy burden to the social health system. The development and progression of NAFLD are affected by the...

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Main Author: CHEN Yiyan
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2020-06-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=10812
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spelling doaj-91f6926b3523455b9c3da4c6c95662372020-11-25T03:13:35ZzhoEditorial Department of Journal of Clinical HepatologyLinchuang Gandanbing Zazhi1001-52561001-52562020-06-0136612211223Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver diseaseCHEN Yiyan0Zhongshan Hospital, Fudan UniversityNonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease in developed countries, and in recent years, the prevalence rate of NAFLD tends to increase in China, which brings heavy burden to the social health system. The development and progression of NAFLD are affected by the interaction between multiple influencing factors including genetic and epigenetic factors, transcription factors, hormones, nutrition, and environmental factors. This article reviews the research advances in the role of nuclear receptor in the pathogenesis of NAFLD, in order to deepen the understanding of this disease.http://www.lcgdbzz.org/qk_content.asp?id=10812
collection DOAJ
language zho
format Article
sources DOAJ
author CHEN Yiyan
spellingShingle CHEN Yiyan
Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
Linchuang Gandanbing Zazhi
author_facet CHEN Yiyan
author_sort CHEN Yiyan
title Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
title_short Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
title_full Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
title_fullStr Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
title_full_unstemmed Application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
title_sort application of nuclear receptor in pathogenesis research and drug development for nonalcoholic fatty liver disease
publisher Editorial Department of Journal of Clinical Hepatology
series Linchuang Gandanbing Zazhi
issn 1001-5256
1001-5256
publishDate 2020-06-01
description Nonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease in developed countries, and in recent years, the prevalence rate of NAFLD tends to increase in China, which brings heavy burden to the social health system. The development and progression of NAFLD are affected by the interaction between multiple influencing factors including genetic and epigenetic factors, transcription factors, hormones, nutrition, and environmental factors. This article reviews the research advances in the role of nuclear receptor in the pathogenesis of NAFLD, in order to deepen the understanding of this disease.
url http://www.lcgdbzz.org/qk_content.asp?id=10812
work_keys_str_mv AT chenyiyan applicationofnuclearreceptorinpathogenesisresearchanddrugdevelopmentfornonalcoholicfattyliverdisease
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