p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression
AMPA receptors mediate excitatory synaptic transmission and are involved in synaptic plasticity. The authors show that p97 interacts with the GluA1 subunit of AMPA receptors, promotes the formation of GluA1 homomeric AMPA receptors, and regulates AMPA receptor trafficking during synaptic plasticity.
Bibliographic Details
| Main Authors: |
Yuan Ge,
Meng Tian,
Lidong Liu,
Tak Pan Wong,
Bo Gong,
Dongchuan Wu,
Taesup Cho,
Shujun Lin,
Jürgen Kast,
Jie Lu,
Yu Tian Wang |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2019-09-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-019-12096-7
|
|---|
