Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling

Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling

Background: This study aimed to evaluate the protective effect and mechanisms of remote limb ischaemic postconditioning (RIPostC) against myocardial ischaemia/reperfusion (IR) injury. Methods: Male mice underwent 45 min of coronary artery occlusion followed by 2 h of reperfusion. RIPostC was achieve...

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Bibliographic Details
Main Authors:	Sumin Gao, Leyun Zhan, Zhengchao Yang, Ruili Shi, Haobo Li, Zhengyuan Xia, Shiying Yuan, Qing-ping Wu, Tingting Wang, Shanglong Yao
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2017-10-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Remote limb ischaemic postconditioning JAK/STAT3 Akt ENOS Nrf2 HO-1
Online Access:	https://www.karger.com/Article/FullText/481755

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