Functional Diversity of p53 in Human and Wild Animals

Functional Diversity of p53 in Human and Wild Animals

The common understanding of p53 function is a genome guardian, which is activated by diverse stresses stimuli and mediates DNA repair, apoptosis, and cell cycle arrest. Increasing evidence has demonstrated p53 new cellular functions involved in abundant endocrine and metabolic response for maintaini...

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Bibliographic Details
Main Authors: Yi Li, Meng-Chen Zhang, Xiao-Kang Xu, Yang Zhao, Chatoo Mahanand, Tao Zhu, Hong Deng, Eviatar Nevo, Ji-Zeng Du, Xue-Qun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
p53
mutation
metastasis
transcriptional factor
stress
variation
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00152/full

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