Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells.

Pancreatic cancer is a deadly disease and has the worst prognosis among almost all cancers and is in dire need of new and improved therapeutic strategies. Conditioning of tumor cells with chemotherapeutic drug has been shown to enhance the anti-tumor effects of cancer vaccines and adoptive cell ther...

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Bibliographic Details
Main Authors: Archana Thakur, Lawrence G Lum, Dana Schalk, Asfar Azmi, Sanjeev Banerjee, Fazlul H Sarkar, Ramzi Mohommad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3501501?pdf=render