Dendritic cells pulsed with placental gp96 promote tumor-reactive immune responses.

Defining and loading of immunogenic and safe cancer antigens remain a major challenge for designing dendritic cell (DC)-based cancer vaccines. In this study, we defined a prototype strategy of using DC-based vaccines pulsed with placenta-derived heat shock protein gp96 to induces anti-tumor T cell r...

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Bibliographic Details
Main Authors: Huaguo Zheng, Lanlan Liu, Han Zhang, Fangming Kan, Shuo Wang, Yang Li, Huaqin Tian, Songdong Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211490

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