CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury

CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury

Traumatic brain injury (TBI) is a prevalent head injury worldwide which increases the risk of neurodegenerative diseases. Increased reactive oxygen species (ROS) and inflammatory chemokines after TBI induces secondary effects which damage neurons. Targeting NADPH oxidase or increasing redox systems...

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Bibliographic Details
Main Authors: Man-Hau Ho, Chia-Hung Yen, Tsung-Hsun Hsieh, Tzu-Jen Kao, Jing-Yuan Chiu, Yung-Hsiao Chiang, Barry J. Hoffer, Wen-Chang Chang, Szu-Yi Chou
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Redox Biology
Subjects:
CCL5
Reactive oxygen species (ROS)
NADPH oxidase
Traumatic brain injury
Glutathione peroxidase - 1 (GPX1)
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002263

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http://www.sciencedirect.com/science/article/pii/S2213231721002263

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