Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.

Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas.

Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system (CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to parallel expression and function in normal stem cells. Using RNA in situ hybridization and antibody tools capable of detectin...

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Bibliographic Details
Main Authors: Karl Holmberg Olausson, Cecile L Maire, Sam Haidar, Jason Ling, Emily Learner, Monica Nistér, Keith L Ligon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153667?pdf=render

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