Severe sepsis caused by serious gastrointestinal infection in sJIA patients treated with IL-6 receptor antagonist: a case report

Severe sepsis caused by serious gastrointestinal infection in sJIA patients treated with IL-6 receptor antagonist: a case report

Abstract Background Interleukin (IL)-6 plays an essential role in the pathogenesis of systemic juvenile idiopathic arthritis (sJIA). Tocilizumab (TCZ), a kind of biological agent against both membrane and soluble IL-6 receptor, is the only biological agent approved for the treatment of sJIA in China...

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Bibliographic Details
Main Authors: Meng Xu, Congcong Liu, Lishuang Guo, Sirui Yang
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Pediatrics
Subjects:
Systemic juvenile idiopathic arthritis
Tocilizumab
Gastrointestinal infection
Sepsis
Case report
Online Access:http://link.springer.com/article/10.1186/s12887-020-02032-w

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