miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6.

miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6.

A critical role of the Toll-like receptor(TLR) and its downstream molecules, including IL-1 receptor-associated kinase 1(IRAK1) and tumor necrosis factor receptor- associated factor 6(TRAF6), in the pathogenesis of liver ischemia/reperfusion (I/R) injury has been documented. Recently a microRNA, miR...

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Bibliographic Details
Main Authors: Weiwei Jiang, Liangliang Kong, Qingfeng Ni, Yeting Lu, Wenzhou Ding, Guoqing Liu, Liyong Pu, Weibing Tang, Lianbao Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4079695?pdf=render

Internet

http://europepmc.org/articles/PMC4079695?pdf=render

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