Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer’s disease

Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is characterized by amyloid beta (Aβ) deposits as plaques in the parenchyma and in the walls of cortical and leptomeningeal blood vessels of the brain called cerebral amyloid angiopathy (CAA). It is suggested that CAA type-1, which refers to amyloid deposition in bo...

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Bibliographic Details
Main Authors: David C. Hondius, Kristel N. Eigenhuis, Tjado H. J. Morrema, Roel C. van der Schors, Pim van Nierop, Marianna Bugiani, Ka Wan Li, Jeroen J. M. Hoozemans, August B. Smit, Annemieke J. M. Rozemuller
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Cerebral amyloid angiopathy
Amyloid beta
Alzheimer’s disease
Proteomics
Biomarker
Laser microdissection
Online Access:http://link.springer.com/article/10.1186/s40478-018-0540-2

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