Genetic Variants in Immune Related Genes as Predictors of Responsiveness to BCG Immunotherapy in Metastatic Melanoma Patients

Genetic Variants in Immune Related Genes as Predictors of Responsiveness to BCG Immunotherapy in Metastatic Melanoma Patients

Adjuvant immunotherapy in melanoma patients improves clinical outcomes. However, success is unpredictable due to inherited heterogeneity of immune responses. Inherent immune genes associated with single nucleotide polymorphisms (SNPs) may influence anti-tumor immune responses. We assessed the predic...

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Bibliographic Details
Main Authors: Romela Irene Ramos, Misa A. Shaw, Leland Foshag, Stacey L. Stern, Negin Rahimzadeh, David Elashoff, Dave S. B. Hoon
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
SNP
Bacille Calmette–Guérin
metastatic melanoma
cancer immunology
adjuvant immunotherapy
innate immunity
Online Access:https://www.mdpi.com/2072-6694/13/1/91

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