Production of TNF-α, nitric oxide and hydrogen peroxide by macrophages from mice with paracoccidioidomycosis that were fed a linseed oil-enriched diet

Production of TNF-α, nitric oxide and hydrogen peroxide by macrophages from mice with paracoccidioidomycosis that were fed a linseed oil-enriched diet

Omega-3 polyunsaturated fatty acids (n-3 PUFA) can modulate the immune system and their primary effect is on macrophage function. Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America that is caused by the dimorphic fungus Paracoccidioides brasiliensis (Pb). Macrophages are th...

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Bibliographic Details
Main Authors: Sheisa Cyléia Sargi, Márcia Machado de Oliveira Dalalio, Jesuí Vergílio Visentainer, Rafael Campos Bezerra, João Ângelo de Lima Perini, Flávia Braidotti Stevanato, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
macrophages
Paracoccidioides brasiliensis
cytokines
n-3 polyunsaturated fatty acids
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000300003&lng=en&tlng=en

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