TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors

TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors

Tumor necrosis factor (TNF) is widely accepted as a tumor-suppressive cytokine via its ubiquitous receptor TNF receptor 1 (TNFR1). The other receptor, TNFR2, is not only expressed on some tumor cells but also on suppressive immune cells, including regulatory T cells and myeloid-derived suppressor ce...

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Bibliographic Details
Main Authors: Yuqiao Sheng, Feng Li, Zhihai Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
tumor necrosis factor
TNF receptor 2
tumor
myeloid-derived suppressor cells
regulatory T cells
macrophages
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01170/full

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