Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes

<p>Abstract</p> <p>Maintaining the integrity of sperm DNA is vital to reproduction and male fertility. Sperm contain a number of molecules and pathways for the repair of base excision, base mismatches and DNA strand breaks. The presence of Poly (ADP-ribose) polymerase (PARP), a DNA...

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Bibliographic Details
Main Authors: Sarkar Oli, Sharma Rakesh K, Mahfouz Reda Z, Agarwal Ashok, Mangrola Devna, Mathur Premendu P
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/7/1/143