OX40 agonists and combination immunotherapy: putting the pedal to the metal

Recent studies have highlighted the therapeutic efficacy of immunotherapy, a class of cancer treatments that utilize the patient’s own immune system to destroy cancerous cells. Within a tumor the presence of a family of negative regulatory molecules, collectively known as checkpoint inhibitors, can...

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Bibliographic Details
Main Authors: Stefanie N Linch, Michael J McNamara, William L. Redmond
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Oncology
Subjects:
KIR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00034/full