Dose-response efficacy and mechanisms of orally administered CLA-producing Bifidobacterium breve CCFM683 on DSS-induced colitis in mice

This study designed to explore the dose-effect relationship of CCFM683 in relieving colitis and investigate the mechanisms involved. Specifically, the concentration of mucin2, goblet cells and tight junction proteins were significantly up-regulated by 1010 and 109 cfu/day CCFM683. Moreover, interleu...

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Bibliographic Details
Main Authors: Yang Chen, Yan Jin, Catherine Stanton, R. Paul Ross, Zhi Wang, Jianxin Zhao, Hao Zhang, Bo Yang, Wei Chen
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620304692