Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy

Over the past few decades, the synthetic development of ultra-small nanoparticles has become an important strategy in nano-medicine, where smaller-sized nanoparticles are known to be more easily excreted from the body, greatly reducing the risk caused by introducing nano-theranostic agents. Gold nan...

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Main Authors: Lu An, Yuanyuan Wang, Qiwei Tian, Shiping Yang
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/10/12/1372
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spelling doaj-90ff44ce26e24666a42c46f109ca7ed82020-11-24T20:46:28ZengMDPI AGMaterials1996-19442017-11-011012137210.3390/ma10121372ma10121372Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer TherapyLu An0Yuanyuan Wang1Qiwei Tian2Shiping Yang3The Key Laboratory of Resource Chemistry of the Ministry of Education, the Shanghai Key Laboratory of Rare Earth Functional Materials, and the Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, ChinaThe Key Laboratory of Resource Chemistry of the Ministry of Education, the Shanghai Key Laboratory of Rare Earth Functional Materials, and the Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, ChinaThe Key Laboratory of Resource Chemistry of the Ministry of Education, the Shanghai Key Laboratory of Rare Earth Functional Materials, and the Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, ChinaThe Key Laboratory of Resource Chemistry of the Ministry of Education, the Shanghai Key Laboratory of Rare Earth Functional Materials, and the Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, ChinaOver the past few decades, the synthetic development of ultra-small nanoparticles has become an important strategy in nano-medicine, where smaller-sized nanoparticles are known to be more easily excreted from the body, greatly reducing the risk caused by introducing nano-theranostic agents. Gold nanorods are one of the most important nano-theranostic agents because of their special optical and electronic properties. However, the large size (diameter > 6 nm) of most obtained gold nanorods limits their clinical application. In recent years, more and more researchers have begun to investigate the synthesis and application of small gold nanorods (diameter < 6 nm), which exhibit similar optical and electronic properties as larger gold nanorods. In this review, we summarize the recent advances of synthesis of the small gold nanorods and their application for near-infrared light-mediated bio-imaging and cancer therapy.https://www.mdpi.com/1996-1944/10/12/1372small gold nanorodsseedlessbiological imagingcancer therapy
collection DOAJ
language English
format Article
sources DOAJ
author Lu An
Yuanyuan Wang
Qiwei Tian
Shiping Yang
spellingShingle Lu An
Yuanyuan Wang
Qiwei Tian
Shiping Yang
Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
Materials
small gold nanorods
seedless
biological imaging
cancer therapy
author_facet Lu An
Yuanyuan Wang
Qiwei Tian
Shiping Yang
author_sort Lu An
title Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
title_short Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
title_full Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
title_fullStr Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
title_full_unstemmed Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy
title_sort small gold nanorods: recent advances in synthesis, biological imaging, and cancer therapy
publisher MDPI AG
series Materials
issn 1996-1944
publishDate 2017-11-01
description Over the past few decades, the synthetic development of ultra-small nanoparticles has become an important strategy in nano-medicine, where smaller-sized nanoparticles are known to be more easily excreted from the body, greatly reducing the risk caused by introducing nano-theranostic agents. Gold nanorods are one of the most important nano-theranostic agents because of their special optical and electronic properties. However, the large size (diameter > 6 nm) of most obtained gold nanorods limits their clinical application. In recent years, more and more researchers have begun to investigate the synthesis and application of small gold nanorods (diameter < 6 nm), which exhibit similar optical and electronic properties as larger gold nanorods. In this review, we summarize the recent advances of synthesis of the small gold nanorods and their application for near-infrared light-mediated bio-imaging and cancer therapy.
topic small gold nanorods
seedless
biological imaging
cancer therapy
url https://www.mdpi.com/1996-1944/10/12/1372
work_keys_str_mv AT luan smallgoldnanorodsrecentadvancesinsynthesisbiologicalimagingandcancertherapy
AT yuanyuanwang smallgoldnanorodsrecentadvancesinsynthesisbiologicalimagingandcancertherapy
AT qiweitian smallgoldnanorodsrecentadvancesinsynthesisbiologicalimagingandcancertherapy
AT shipingyang smallgoldnanorodsrecentadvancesinsynthesisbiologicalimagingandcancertherapy
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