Efficacy of immunotherapy in lung cancer with co-occurring mutations in NOTCH and homologous repair genes

Efficacy of immunotherapy in lung cancer with co-occurring mutations in NOTCH and homologous repair genes

Background Immune checkpoint inhibitors (ICIs) provide significant survival benefits in non-small cell lung cancer (NSCLC). Nevertheless, while some patients obtain a prolonged benefit, a non-negligible fraction of patients experiences an ultrarapid disease progression. Identifying specific molecula...

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Main Authors: Andrea Botticelli, Irene Terrenato, Marco Mazzotta, Mario Occhipinti, Daniele Marinelli, Stefano Scalera, Francesca Sperati, Francesco Rizzo, Giorgia Scafetta, Arianna Di Napoli, Eriseld Krasniqi, Laura Pizzuti, Maddalena Barba, Silvia Carpano, Patrizia Vici, Francesca De Nicola, Ludovica Ciuffreda, Frauke Goeman, Andrea Vecchione, Marcello Maugeri-Saccà
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000946.full

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