Influence Of Smoking Habit On Age At Diagnosis Of Breast Cancer

• Main Authors: Rajaei Mehrdad, Omidvari Shapour, Saadat Mostafa
• Format: Article
• Language: English
• Published: Sciendo 2015-09-01
• Series: Serbian Journal of Experimental and Clinical Research
• Subjects: age at diagnosis; breast cancer; smoking habit; starosna dob u trenutku postavljanja dijagnoze; karcinom dojke; pušenje
• Online Access: https://doi.org/10.1515/sjecr-2015-0028

No studies have yet investigated the influence of smoking on age at diagnosis of breast cancer. Therefore, the present study was carried out. This study consisted of 605 females with pathologically confirmed primary adenocarcinoma of the breast and 438 healthy females matched by age. Among our participants, 86 (14.2%) patients and 62 (14.1%) control subjects, respectively, were smokers. Based on a Cox regression model, evidence suggested that smoking status influenced the age at diagnosis of breast cancer (HR=0.78, 95% CI: 0.62-0.99, P=0.040). After stratification of the patients according to their menopausal status, the same results were obtained. The present study indicated that non-smokers have a lower age at diagnosis in comparison with patients who smoke.