Endoplasmic reticulum stress response in an INS-1 pancreatic β-cell line with inducible expression of a folding-deficient proinsulin

Endoplasmic reticulum stress response in an INS-1 pancreatic β-cell line with inducible expression of a folding-deficient proinsulin

<p>Abstract</p> <p>Background</p> <p>Cells respond to endoplasmic reticulum stress (ER) stress by activating the unfolded protein response. To study the ER stress response in pancreatic β-cells we developed a model system that allows for pathophysiological ER stress bas...

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Bibliographic Details
Main Authors: Lai Elida, Siva Madura, Hartley Taila, Teodoro Tracy, Zhang Liling, Volchuk Allen
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/59

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http://www.biomedcentral.com/1471-2121/11/59

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