Gender Related Changes in Gene Expression Induced by Valproic Acid in A Mouse Model of Autism and the Correction by S-adenosyl Methionine. Does It Explain the Gender Differences in Autistic Like Behavior?

Gender Related Changes in Gene Expression Induced by Valproic Acid in A Mouse Model of Autism and the Correction by S-adenosyl Methionine. Does It Explain the Gender Differences in Autistic Like Behavior?

In previous studies we produced autism like behavioral changes in mice by Valproic acid (VPA) with significant differences between genders. S-adenosine methionine (SAM) prevented the autism like behavior in both genders. The expression of 770 genes of pathways involved in neurophysiology and neuropa...

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Bibliographic Details
Main Authors: Liza Weinstein-Fudim, Zivanit Ergaz, Gadi Turgeman, Joseph Yanai, Moshe Szyf, Asher Ornoy
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
asd
epigenetics
mice
postnatal vpa injection
sam
gene expression
nanostring
Online Access:https://www.mdpi.com/1422-0067/20/21/5278

Internet

https://www.mdpi.com/1422-0067/20/21/5278

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