Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling

Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling

Pulmonary fibrosis is a severe and irreversible interstitial pulmonary disease with high mortality and few treatments. Magnesium lithospermate B (MLB) is a hydrosoluble component of <i>Salvia miltiorrhiza</i> and has been reported to have antifibrotic effects in other forms of tissue fib...

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Bibliographic Details
Main Authors: Xin Luo, Qiangqiang Deng, Yaru Xue, Tianwei Zhang, Zhitao Wu, Huige Peng, Lijiang Xuan, Guoyu Pan
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
pulmonary fibrosis
bleomycin
magnesium lithospermate B
transforming growth factor-beta
Smad signaling
Online Access:https://www.mdpi.com/1420-3049/26/6/1715

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