Transcriptome Analysis of Microglia Reveals That the TLR2/IRF7 Signaling Axis Mediates Neuroinflammation After Subarachnoid Hemorrhage

Transcriptome Analysis of Microglia Reveals That the TLR2/IRF7 Signaling Axis Mediates Neuroinflammation After Subarachnoid Hemorrhage

Microglia-mediated neuroinflammatory response in the early brain injury after subarachnoid hemorrhage (SAH) has been reported to have an impact on progress, and the mechanism is not completely understood. Here, we performed genome-wide transcriptome analysis of microglia purified from damaged hemisp...

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Bibliographic Details
Main Authors: Shenbin Xu, Shuhao Mei, Jianan Lu, Haijian Wu, Xiao Dong, Ligen Shi, Jingyi Zhou, Jianmin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
subarachnoid hemorrhage
microglia
flow cytometry
bulk RNA-seq
early brain injury
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.645649/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.645649/full

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