The virtual screening application for searching potential antiviral agents to treat COVID-19 disease

The virtual screening application for searching potential antiviral agents to treat COVID-19 disease

Aim. To provide a brief literature review regarding the structure of the human coronavirus SARS-CoV-2, the mechanism of its replication and the role of viral proteases in this process; to analyze the ability of the known antiviral agents and compounds synthesized de novo in order to bind and inhibit...

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Bibliographic Details
Main Authors:	Volodymyr V. Ivanov, Veronika R. Karpina, Svitlana S. Kovalenko, Ihor E. Kuznetsov, Thierry Langer, Louis J.R.M. Maes, Serhii M. Kovalenko, Larysa V. Evseeva
Format:	Article
Language:	English
Published:	National University of Pharmacy (Kharkiv, Ukraine) 2020-05-01
Series:	Журнал органічної та фармацевтичної хімії
Subjects:	coronavirus infection sars-cov-2 mpro protease 6lu7 molecular docking virtual screening antiviral activity оxadiazole quinazolin-5-ones triazolopyridine
Online Access:	http://ophcj.nuph.edu.ua/article/view/ophcj.20.200019/206089

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