Giant prolactinoma, a case report and review of the literature

A 13 year old boy presented with acute onset of sudden severe headache and visual impairment following a one-year history of intermittent frontal headache. Serum prolactin level was 17532ng/ml (normal 3–24ng/ml). Magnetic resonance imaging showed a large intrasellar mass with suprasellar extension a...

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Main Authors:	Doua K. Al Homyani, Reem A. Al Khalifah, Ikhlass S. Al Tuwaijri, Rushaid N. Al Jurayyan, Nasir A. Al Jurayyan
Format:	Article
Language:	English
Published:	Elsevier 2019-06-01
Series:	Journal of Clinical and Translational Endocrinology Case Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214624518300571

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spelling	doaj-90e0a93468114c25a64a7370b36e64f32020-11-24T21:26:39ZengElsevierJournal of Clinical and Translational Endocrinology Case Reports2214-62452019-06-0112Giant prolactinoma, a case report and review of the literatureDoua K. Al Homyani0Reem A. Al Khalifah1Ikhlass S. Al Tuwaijri2Rushaid N. Al Jurayyan3Nasir A. Al Jurayyan4Endocrine Division, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Corresponding author. Endocrine Division, Department of Pediatric, College of Medicine, PO BOX: 2925, Riyadh 11467, Saudi Arabia.Endocrine Division, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi ArabiaNeurosurgery Division, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Radiology and Medical Imaging, College of Medicine, King Saud University, Riyadh, Saudi ArabiaEndocrine Division, College of Medicine, King Saud University, Riyadh, Saudi ArabiaA 13 year old boy presented with acute onset of sudden severe headache and visual impairment following a one-year history of intermittent frontal headache. Serum prolactin level was 17532ng/ml (normal 3–24ng/ml). Magnetic resonance imaging showed a large intrasellar mass with suprasellar extension and evidence of recent hemorrhage within the mass. Cabergoline was started and laparoscopic trans sphenoidal resection of pituitary adenoma was performed. Six months post therapy, he had complete restoration of right eye vision, and partial restoration of left one. Early surgical intervention in addition to medical therapy in case of pediatric pituitary apoplexy associated with giant prolactinoma might be essential to restore vision. Keywords: Pituitary apoplexy, Giant prolactinoma, Cabergolinehttp://www.sciencedirect.com/science/article/pii/S2214624518300571
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Doua K. Al Homyani Reem A. Al Khalifah Ikhlass S. Al Tuwaijri Rushaid N. Al Jurayyan Nasir A. Al Jurayyan
spellingShingle	Doua K. Al Homyani Reem A. Al Khalifah Ikhlass S. Al Tuwaijri Rushaid N. Al Jurayyan Nasir A. Al Jurayyan Giant prolactinoma, a case report and review of the literature Journal of Clinical and Translational Endocrinology Case Reports
author_facet	Doua K. Al Homyani Reem A. Al Khalifah Ikhlass S. Al Tuwaijri Rushaid N. Al Jurayyan Nasir A. Al Jurayyan
author_sort	Doua K. Al Homyani
title	Giant prolactinoma, a case report and review of the literature
title_short	Giant prolactinoma, a case report and review of the literature
title_full	Giant prolactinoma, a case report and review of the literature
title_fullStr	Giant prolactinoma, a case report and review of the literature
title_full_unstemmed	Giant prolactinoma, a case report and review of the literature
title_sort	giant prolactinoma, a case report and review of the literature
publisher	Elsevier
series	Journal of Clinical and Translational Endocrinology Case Reports
issn	2214-6245
publishDate	2019-06-01
description	A 13 year old boy presented with acute onset of sudden severe headache and visual impairment following a one-year history of intermittent frontal headache. Serum prolactin level was 17532ng/ml (normal 3–24ng/ml). Magnetic resonance imaging showed a large intrasellar mass with suprasellar extension and evidence of recent hemorrhage within the mass. Cabergoline was started and laparoscopic trans sphenoidal resection of pituitary adenoma was performed. Six months post therapy, he had complete restoration of right eye vision, and partial restoration of left one. Early surgical intervention in addition to medical therapy in case of pediatric pituitary apoplexy associated with giant prolactinoma might be essential to restore vision. Keywords: Pituitary apoplexy, Giant prolactinoma, Cabergoline
url	http://www.sciencedirect.com/science/article/pii/S2214624518300571
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Giant prolactinoma, a case report and review of the literature

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