Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells

Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells

<p>Abstract</p> <p>In AtT-20 cells ACTH secretion is regulated by both Ca<sup>2+ </sup>and G proteins. We previously demonstrated that calnuc, an EF-hand Ca<sup>2+ </sup>binding protein which regulates Alzheimer's β-amyloid precursor protein (APP) bioge...

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Bibliographic Details
Main Authors: Huang Haining, Lavoie Christine, Fischer Thierry, Lin Ping, Farquhar Marilyn
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/15

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