Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells

Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells

Abstract Mesenchymal stem cells (MSC) have been shown to improve wound healing and suppress inflammatory immune responses. Newer research also indicates that MSC exhibit antimicrobial activity, although the mechanisms underlying this activity have not been fully elucidated. Therefore, we conducted i...

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Bibliographic Details
Main Authors: Lyndah Chow, Valerie Johnson, Renata Impastato, Jonathan Coy, Alyssa Strumpf, Steven Dow
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Stem Cells Translational Medicine
Subjects:
antibacterial
cytokines
infection
neutrophil
peptides
stem cells
Online Access:https://doi.org/10.1002/sctm.19-0092

Internet

https://doi.org/10.1002/sctm.19-0092

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