Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis

Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis

Abstract Background Gestational diabetes mellitus (GDM) is the most common medical complication of pregnancy. CircRNA polyribonucleotide nucleotidyltransferase 1 (circ-PNPT1) has been found to be abnormally expressed in GDM patients. However, function and mechanism of circ-PNPT1 in GDM remain largel...

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Bibliographic Details
Main Authors: Li Zhang, Ming Zeng, Fei Tang, Jun Chen, Dongmei Cao, Ze-nan Tang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Circ-PNPT1
miR-889-3p
PAK1
Gestational diabetes mellitus
Exosomes
Online Access:https://doi.org/10.1186/s13098-021-00678-9

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