RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

The limited availability of high-resolution 3D RNA structures for model training limits RNA secondary structure prediction. Here, the authors overcome this challenge by pre-training a DNN on a large set of predicted RNA structures and using transfer learning with high-resolution structures.

Bibliographic Details
Main Authors: Jaswinder Singh, Jack Hanson, Kuldip Paliwal, Yaoqi Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13395-9