Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials

Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials

Abstract Background Many patients with Alzheimer’s disease (AD) are physically frail or have substantial functional impairments. There is growing evidence that such patients are at higher risk for medication-induced adverse events. Furthermore, frailty seems to be more predictive of poor clinical ou...

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Bibliographic Details
Main Authors: M. Seibert, V. Mühlbauer, J. Holbrook, S. Voigt-Radloff, S. Brefka, D. Dallmeier, M. Denkinger, C. Schönfeldt-Lecuona, S. Klöppel, C. A. F. von Arnim
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Frail elderly
Alzheimer’s disease
Dementia
BPSD
Systematic review
Drug therapy
Online Access:https://doi.org/10.1186/s13195-021-00867-8

Internet

https://doi.org/10.1186/s13195-021-00867-8

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