Strategies in megasynthase engineering – fatty acid synthases (FAS) as model proteins
Megasynthases are large multienzyme proteins that produce a plethora of important natural compounds by catalyzing the successive condensation and modification of precursor units. Within the class of megasynthases, polyketide synthases (PKS) are responsible for the production of a large spectrum of b...
Main Authors: | Manuel Fischer, Martin Grininger |
---|---|
Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2017-06-01
|
Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.13.119 |
Similar Items
-
Benzalacetone Synthase
by: Ikuro eAbe
Published: (2012-03-01) -
Structural and functional studies on 6-methylsalicylic acid synthase from Penicillium patulum and holo-acyl carrier protein synthase from Escherichia coli
by: Johnson, Neil Ian
Published: (2001) -
PUFA-synthase-specific PPTase enhanced the polyunsaturated fatty acid biosynthesis via the polyketide synthase pathway in Aurantiochytrium
by: Sen Wang, et al.
Published: (2020-08-01) -
Synthesis of acridone derivatives via heterologous expression of a plant type III polyketide synthase in Escherichia coli
by: Gyu-Sik Choi, et al.
Published: (2020-03-01) -
Fatty Acid Synthase: An Emerging Target in Cancer
by: Chee Wai Fhu, et al.
Published: (2020-08-01)